Possibilities for Immunomodulation in Congenital Toxoplasmosis
نویسندگان
چکیده
منابع مشابه
Congenital toxoplasmosis.
Congenital toxoplasmosis results from the transplacental transmission of the parasite Toxoplasma gondii after a maternal infection acquired in pregnancy. Prevalence of congenital infection ranges from 0.1 to 0.3 per 1000 live births. The maternal-fetal transmission rate increases with gestational age at maternal seroconversion, from less than 15% at 13 weeks of gestation to over 70% at 36 weeks...
متن کاملCongenital toxoplasmosis.
The history of toxoplasmosis began in 1923 with the F first published description of a human case, a congenitally infected baby. Toxoplasma gondii had been recognised 15 years earlier, but it was not until 1%96 that the life cycle of this protozoan parasite was understood, with the discovery that the definitive host : was any member of the cat family (fig 1).' 2 _ Despite extensive clinical and...
متن کامل[Congenital toxoplasmosis].
Since congenital toxoplasmosis was first recognized as a human infection 18 years ago, it has been found in many parts of the world, and, following the first report by Jacoby and Sagorin in 1948, over 50 cases have been recorded in the British literature. Only four of the reports from this country concern the findings in fatal cases (Cathie and Dudgeon, 1949; Valentine, 1952; Valentine, Lane, B...
متن کاملHLA typing in congenital toxoplasmosis.
HLA-A, HLA-B, HLA-C, and HLA-D typing was performed in 47 mothers of patients suffering from ocular toxoplasmosis to investigate whether an immunogenetic predisposition exists for developing congenital toxoplasmosis in their offspring. No significant association between any HLA antigen was observed in the mothers of patients with ocular toxoplasmosis, although a total absence of the HLA-B51 ant...
متن کاملCongenital toxoplasmosis in the newborn.
A majority of the recorded cases of congenital toxoplasmosis have shown either clinical evidence of damage to the central nervous system at birth or have developed such signs after the first few weeks of life. The purpose of this report is to describe two cases, occurring within a short period in one maternity unit, showing at birth signs of generalized disease. One infant lived only a few minu...
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ژورنال
عنوان ژورنال: Journal of Infectious Diseases
سال: 2016
ISSN: 0022-1899,1537-6613
DOI: 10.1093/infdis/jiw210